Effects of T cell leptin signaling on systemic glucose tolerance and T cell responses in obesity

BACKGROUND/OBJECTIVES: Leptin is an adipokine secreted in proportion to adipocyte mass and is therefore increased in obesity. Leptin signaling has been shown to directly promote inflammatory T helper 1 (Th1) and T helper 17 (Th17) cell number and function. Since T cells have a critical role in drivi...

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Detalles Bibliográficos
Autores principales: Kiernan, Kaitlin, Nichols, Amanda G., Alwarawrah, Yazan, MacIver, Nancie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241364/
https://www.ncbi.nlm.nih.gov/pubmed/37276236
http://dx.doi.org/10.1371/journal.pone.0286470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241364/
https://www.ncbi.nlm.nih.gov/pubmed/37276236
http://dx.doi.org/10.1371/journal.pone.0286470

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