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Globoside and the mucosal pH mediate parvovirus B19 entry through the epithelial barrier

Parvovirus B19 (B19V) is transmitted primarily via the respiratory route, however, the mechanism involved remains unknown. B19V targets a restricted receptor expressed in erythroid progenitor cells in the bone marrow. However, B19V shifts the receptor under acidic conditions and targets the widely e...

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Detalles Bibliográficos
Autores principales: Suter, Corinne, Colakovic, Minela, Bieri, Jan, Gultom, Mitra, Dijkman, Ronald, Ros, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241365/
https://www.ncbi.nlm.nih.gov/pubmed/37220143
http://dx.doi.org/10.1371/journal.ppat.1011402