Rho-associated protein kinase 1 inhibition in hepatocytes attenuates nonalcoholic steatohepatitis

NASH is the progressive form of NAFLD characterized by lipotoxicity, hepatocyte injury, tissue inflammation, and fibrosis. Previously, Rho-associated protein kinase (ROCK) 1 has been implicated in lipotoxic signaling in hepatocytes in vitro and high-fat diet-induced lipogenesis in vivo. However, whe...

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Detalles Bibliográficos
Autores principales: Dohnalkova, Ester, Bayer, Rachel L., Guo, Qianqian, Bamidele, Adebowale O., Kim Lee, Hyun Se, Valenzuela-Pérez, Lucía, Krishnan, Anuradha, Pavelko, Kevin D., Guisot, Nicolas E.S., Bunyard, Peter, Kim, Young-Bum, Ibrahim, Samar H., Gores, Gregory J., Hirsova, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241501/
https://www.ncbi.nlm.nih.gov/pubmed/37267252
http://dx.doi.org/10.1097/HC9.0000000000000171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241501/
https://www.ncbi.nlm.nih.gov/pubmed/37267252
http://dx.doi.org/10.1097/HC9.0000000000000171

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