Microcephaly-associated protein WDR62 shuttles from the Golgi apparatus to the spindle poles in human neural progenitors

WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions. Recessive mutations in WDR62 cause structural brain abnormalities and account for the second most common cause of autosomal recessive primary microcephaly (MCPH), indicating WDR62 as a critical hub for human brain develo...

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Detalles Bibliográficos
Autores principales: Dell'Amico, Claudia, Angulo Salavarria, Marilyn M, Takeo, Yutaka, Saotome, Ichiko, Dell'Anno, Maria Teresa, Galimberti, Maura, Pellegrino, Enrica, Cattaneo, Elena, Louvi, Angeliki, Onorati, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241521/
https://www.ncbi.nlm.nih.gov/pubmed/37272619
http://dx.doi.org/10.7554/eLife.81716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241521/
https://www.ncbi.nlm.nih.gov/pubmed/37272619
http://dx.doi.org/10.7554/eLife.81716

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