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A circadian clock translational control mechanism targets specific mRNAs to cytoplasmic messenger ribonucleoprotein granules

Phosphorylation of Neurospora crassa eukaryotic initiation factor 2 α (eIF2α), a conserved translation initiation factor, is clock controlled. To determine the impact of rhythmic eIF2α phosphorylation on translation, we performed temporal ribosome profiling and RNA sequencing (RNA-seq) in wild-type...

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Detalles Bibliográficos
Autores principales: Castillo, Kathrina D., Wu, Cheng, Ding, Zhaolan, Lopez-Garcia, Osiris K., Rowlinson, Emma, Sachs, Matthew S., Bell-Pedersen, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241597/
https://www.ncbi.nlm.nih.gov/pubmed/36577368
http://dx.doi.org/10.1016/j.celrep.2022.111879