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ABHD17C, a metabolic and immune-related gene signature, predicts prognosis and anti-PD1 therapy response in pancreatic cancer

BACKGROUND: PDAC is a highly malignant and immune-suppressive tumor, posing great challenges to therapy. METHODS: In this study, we utilized multi-center RNA sequencing and non-negative matrix factorization clustering (NMF) to identify a group of metabolism-related genes that could effectively predi...

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Detalles Bibliográficos
Autores principales: Zhang, Weihao, Xie, Yongjie, Yu, Xin, Liu, Changfu, Gao, Wei, Xing, Wenge, Si, Tongguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241759/
https://www.ncbi.nlm.nih.gov/pubmed/37273016
http://dx.doi.org/10.1007/s12672-023-00690-7