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The Clinical and Prognostic Significance of Ribonucleotide Reductase Subunits RRM1 and RRM2 mRNA Levels in Patients with Chronic Lymphocytic Leukemia

Ribonucleotide Reductase (RNR) converts ribonucleotides to deoxyribonucleotides required for DNA replication and repair. RNR consists of subunits M1 and M2. It has been studied as a prognostic factor in several solid tumors and in chronic hematological malignancies, but not in chronic lymphocytic le...

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Detalles Bibliográficos
Autores principales: Chatzidavid, Sevastianos, Kontandreopoulou, Christina-Nefeli, Diamantopoulos, Panagiotis T., Giannakopoulou, Nefeli, Katsiampoura, Panagiota, Stafylidis, Christos, Dryllis, Georgios, Kyrtsonis, Marie-Christine, Dimou, Maria, Panayiotidis, Panayiotis, Viniou, Nora-Athina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241768/
https://www.ncbi.nlm.nih.gov/pubmed/36811764
http://dx.doi.org/10.1007/s44228-023-00033-x