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A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest
Enhancer-promoter interactions preferentially occur within boundary-insulated topologically associating domains (TADs), limiting inter-TAD interactions. Enhancer clusters in linear proximity, termed super-enhancers (SEs), ensure high target gene expression levels. Little is known about SE topologica...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241789/ https://www.ncbi.nlm.nih.gov/pubmed/37277355 http://dx.doi.org/10.1038/s41467-023-38953-0 |