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A multiple super-enhancer region establishes inter-TAD interactions and controls Hoxa function in cranial neural crest

Enhancer-promoter interactions preferentially occur within boundary-insulated topologically associating domains (TADs), limiting inter-TAD interactions. Enhancer clusters in linear proximity, termed super-enhancers (SEs), ensure high target gene expression levels. Little is known about SE topologica...

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Detalles Bibliográficos
Autores principales: Kessler, Sandra, Minoux, Maryline, Joshi, Onkar, Ben Zouari, Yousra, Ducret, Sebastien, Ross, Fiona, Vilain, Nathalie, Salvi, Adwait, Wolff, Joachim, Kohler, Hubertus, Stadler, Michael B., Rijli, Filippo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241789/
https://www.ncbi.nlm.nih.gov/pubmed/37277355
http://dx.doi.org/10.1038/s41467-023-38953-0