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Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times

Nitroxides are widely used as probes and polarization transfer agents in spectroscopy and imaging. These applications require high stability towards reducing biological environments, as well as beneficial relaxation properties. While the latter is provided by spirocyclic groups on the nitroxide scaf...

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Detalles Bibliográficos
Autores principales: Sowiński, Mateusz P., Gahlawat, Sahil, Lund, Bjarte A., Warnke, Anna-Luisa, Hopmann, Kathrin H., Lovett, Janet E., Haugland, Marius M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241799/
https://www.ncbi.nlm.nih.gov/pubmed/37277501
http://dx.doi.org/10.1038/s42004-023-00912-7