Technical development and validation of a clinically applicable microenvironment classifier as a biomarker of tumour hypoxia for soft tissue sarcoma

BACKGROUND: Soft tissue sarcomas (STS) are rare, heterogeneous tumours and biomarkers are needed to inform management. We previously derived a prognostic tumour microenvironment classifier (24-gene hypoxia signature). Here, we developed/validated an assay for clinical application. METHODS: Technical...

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Detalles Bibliográficos
Autores principales: Forker, Laura J., Bibby, Becky, Yang, Lingjian, Lane, Brian, Irlam, Joely, Mistry, Hitesh, Khan, Mairah, Valentine, Helen, Wylie, James, Shenjere, Patrick, Leahy, Michael, Gaunt, Piers, Billingham, Lucinda, Seddon, Beatrice M., Grimer, Rob, Robinson, Martin, Choudhury, Ananya, West, Catharine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241814/
https://www.ncbi.nlm.nih.gov/pubmed/37085598
http://dx.doi.org/10.1038/s41416-023-02265-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241814/
https://www.ncbi.nlm.nih.gov/pubmed/37085598
http://dx.doi.org/10.1038/s41416-023-02265-3

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