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Irradiation plus myeloid-derived suppressor cell-targeted therapy for overcoming treatment resistance in immunologically cold urothelial carcinoma

BACKGROUND: Radiotherapy (RT) has recently been highlighted as a partner of immune checkpoint inhibitors. The advantages of RT include activation of lymphocytes while it potentially recruits immunosuppressive cells, such as myeloid-derived suppressor cells (MDSCs). This study aimed to investigate th...

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Detalles Bibliográficos
Autores principales: Yamamoto, Shoma, Kato, Minoru, Takeyama, Yuji, Azuma, Yukari, Yukimatsu, Nao, Hirayama, Yukiyoshi, Otoshi, Taiyo, Yamasaki, Takeshi, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki, Uchida, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241820/
https://www.ncbi.nlm.nih.gov/pubmed/37069346
http://dx.doi.org/10.1038/s41416-023-02244-8