Cargando…

Irradiation plus myeloid-derived suppressor cell-targeted therapy for overcoming treatment resistance in immunologically cold urothelial carcinoma

BACKGROUND: Radiotherapy (RT) has recently been highlighted as a partner of immune checkpoint inhibitors. The advantages of RT include activation of lymphocytes while it potentially recruits immunosuppressive cells, such as myeloid-derived suppressor cells (MDSCs). This study aimed to investigate th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamamoto, Shoma, Kato, Minoru, Takeyama, Yuji, Azuma, Yukari, Yukimatsu, Nao, Hirayama, Yukiyoshi, Otoshi, Taiyo, Yamasaki, Takeshi, Fujioka, Masaki, Gi, Min, Wanibuchi, Hideki, Uchida, Junji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241820/ https://www.ncbi.nlm.nih.gov/pubmed/37069346 http://dx.doi.org/10.1038/s41416-023-02244-8

Ejemplares similares

Successful case of olaparib treatment for castration-resistant prostate cancer with multiple DNA repair gene mutations: Use of comprehensive genome profiling for treatment-refractory cases
por: Hirayama, Yukiyoshi, et al.
Publicado: (2022)

Carbonic anhydrase 2 is a novel invasion‐associated factor in urinary bladder cancers
por: Tachibana, Hirokazu, et al.
Publicado: (2017)

Role of deltaNp63(pos) CD44v(pos) cells in the development of N‐nitroso‐tris‐chloroethylurea‐induced peripheral‐type mouse lung squamous cell carcinomas
por: Yamano, Shotaro, et al.
Publicado: (2016)

Steroid sulfatase promotes invasion through epithelial-mesenchymal transition and predicts the progression of bladder cancer
por: Shimizu, Yasuomi, et al.
Publicado: (2018)

Anti‐PD‐L1 treatment enhances antitumor effect of everolimus in a mouse model of renal cell carcinoma
por: Hirayama, Yukiyoshi, et al.
Publicado: (2016)

The carbonic anhydrase inhibitor acetazolamide inhibits urinary bladder cancers via suppression of β‐catenin signaling
por: Matsue, Taisuke, et al.
Publicado: (2022)

Response biomarkers of inhalation exposure to cigarette smoke in the mouse lung
por: Suzuki, Shugo, et al.
Publicado: (2022)

DNA Methylation Aberrations in Dimethylarsinic Acid-Induced Bladder Carcinogenesis
por: Yamamoto, Tomoki, et al.
Publicado: (2023)

ABO-incompatible kidney transplantation in elderly patients over 60 years of age
por: Uchida, Junji, et al.
Publicado: (2012)

Androgen Receptor Splice Variant 7 Drives the Growth of Castration Resistant Prostate Cancer without Being Involved in the Efficacy of Taxane Chemotherapy
por: Shimizu, Yasuomi, et al.
Publicado: (2018)

A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab
por: Kanamaru, Tomohiro, et al.
Publicado: (2014)

Cytoplasmic Accumulation of Heterogeneous Nuclear Ribonucleoprotein K Strongly Promotes Tumor Invasion in Renal Cell Carcinoma Cells
por: Otoshi, Taiyo, et al.
Publicado: (2015)

Desensitization: Overcoming the Immunologic Barriers to Transplantation
por: Sethi, Supreet, et al.
Publicado: (2017)

Acquired resistance to trastuzumab/pertuzumab or to T‐DM1 in vivo can be overcome by HER2 kinase inhibition with TAS0728
por: Irie, Hiroki, et al.
Publicado: (2020)

Evaluation of the Modifying Effect of Inhalation of Mainstream Cigarette Smoke on Mouse Bladder Carcinogenesis
por: Kato, Minoru, et al.
Publicado: (2013)

Ethanol-Extracted Brazilian Propolis Exerts Protective Effects on Tumorigenesis in Wistar Hannover Rats
por: Kakehashi, Anna, et al.
Publicado: (2016)

Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis
por: Kakehashi, Anna, et al.
Publicado: (2017)

Quantitative Approaches to Assess Key Carcinogenic Events of Genotoxic Carcinogens
por: Fukushima, Shoji, et al.
Publicado: (2018)

mTOR Activation in Liver Tumors Is Associated with Metabolic Syndrome and Non-Alcoholic Steatohepatitis in Both Mouse Models and Humans
por: Okuno, Takahiro, et al.
Publicado: (2018)

A chronic toxicity study of diphenylarsinic acid in the drinking water of C57BL/6J mice for 52 weeks
por: Yamaguchi, Takashi, et al.
Publicado: (2019)

A carcinogenicity study of diphenylarsinic acid in C57BL/6J mice in drinking water for 78 weeks
por: Yamaguchi, Takashi, et al.
Publicado: (2022)

Advanced Urothelial Carcinoma: Overcoming Treatment Resistance through Novel Treatment Approaches
por: Bambury, Richard M., et al.
Publicado: (2013)

Editorial Comment from Dr Hirayama and Dr Iguchi to Cranial nerve palsy caused by metastasis to the skull base in patients with castration‐resistant prostate cancer: Three case reports
por: Hirayama, Yukiyoshi, et al.
Publicado: (2021)

Editorial Comment to Nonmetastatic castration‐resistant prostate cancer treated with salvage focal brachytherapy after external beam radiotherapy
por: Hirayama, Yukiyoshi, et al.
Publicado: (2021)

Immunological monitoring in ICU patients: immunomodulation for compromised host
por: Takeyama, N, et al.
Publicado: (2001)

Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells
por: Jiménez-Guerrero, Rocío, et al.
Publicado: (2018)

Diphenylarsinic acid exerts promotion effects on hepatobiliary carcinogenesis in a rat medium-term multiorgan carcinogenicity bioassay
por: Ishii, Naomi, et al.
Publicado: (2016)

Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital
por: Kakehashi, Anna, et al.
Publicado: (2017)

Suppressor Cells in Human Cancer: Immunology Series Volume 14
por: Potter, M. R.
Publicado: (1982)

Regulation of the Tumor Suppressor FOXO3 by the Thromboxane-A(2) Receptors in Urothelial Cancer
por: Sobolesky, Philip M., et al.
Publicado: (2014)

Overcoming resistance to immunotherapy by targeting GPR84 in myeloid-derived suppressor cells
por: Qin, Guohui, et al.
Publicado: (2023)

Dichotomy between the induction of suppressor cells and immunologic tolerance by adult thymectomy
Publicado: (1980)

Post-operative urothelial recurrence in patients with upper urinary tract urothelial carcinoma managed by radical nephroureterectomy with an ipsilateral bladder cuff: Minimal prognostic impact in comparison with non-urothelial recurrence and other clinical indicators
por: TAKAHARA, KIYOSHI, et al.
Publicado: (2013)

Overcoming Immunological Challenges Limiting Capsid-Mediated Gene Therapy With Machine Learning
por: Wec, Anna Z., et al.
Publicado: (2021)

Editorial: Strategies to overcome tumor evasion and resistance to immunotherapies by targeting immune suppressor cells
por: Saida, Yu, et al.
Publicado: (2023)

Establishment and characterization of urothelial carcinoma cell lines with and without BRAF mutation (V595E) in dogs
por: Yamasaki, Hirofumi, et al.
Publicado: (2022)

Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer
por: Bilgrami, Shumaila M, et al.
Publicado: (2014)

Recent advances in medical therapy for metastatic urothelial cancer
por: Yuasa, Takeshi, et al.
Publicado: (2018)

Genetic Vaccination as a Flexible Tool to Overcome the Immunological Complexity of Invasive Fungal Infections
por: Luberto, Laura, et al.
Publicado: (2021)

BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression
por: Kim, Se Hyun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2f7j1gc2hm6rvns2oaa1ait4u1