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Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is characterized by progressive biliary inflammation and fibrosis. Although gut commensals are associated with PSC, their causative roles and therapeutic strategies remain elusive. Here we detect abundant Klebsiella pneumoniae (Kp) and Enterococcus gallinarum in...

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Detalles Bibliográficos
Autores principales: Ichikawa, Masataka, Nakamoto, Nobuhiro, Kredo-Russo, Sharon, Weinstock, Eyal, Weiner, Iddo Nadav, Khabra, Efrat, Ben-Ishai, Noa, Inbar, Dana, Kowalsman, Noga, Mordoch, Ron, Nicenboim, Julian, Golembo, Myriam, Zak, Naomi, Jablonska, Jagoda, Sberro-Livnat, Hila, Navok, Sharon, Buchshtab, Nufar, Suzuki, Takahiro, Miyamoto, Kentaro, Teratani, Toshiaki, Fujimori, Sota, Aoto, Yoshimasa, Konda, Mikiko, Hayashi, Naoki, Chu, Po-Sung, Taniki, Nobuhito, Morikawa, Rei, Kasuga, Ryosuke, Tabuchi, Takaya, Sugimoto, Shinya, Mikami, Yohei, Shiota, Atsushi, Bassan, Merav, Kanai, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241881/
https://www.ncbi.nlm.nih.gov/pubmed/37277351
http://dx.doi.org/10.1038/s41467-023-39029-9