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Screening properties of trend tests in genetic association studies

In genome-wide association study, extracting disease-associated genetic variants among millions of single nucleotide polymorphisms is of great importance. When the response is a binary variable, the Cochran-Armitage trend tests and associated MAX test are among the most widely used methods for assoc...

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Detalles Bibliográficos
Autores principales: Jiang, Zhenzhen, Guo, Hongping, Wang, Jinjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241885/
https://www.ncbi.nlm.nih.gov/pubmed/37277435
http://dx.doi.org/10.1038/s41598-023-35929-4