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MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways

Gene fusions caused by cytogenetic aberrations play important roles in the initiation and progression of cancers. The recurrent MTAP-ANRIL fusion gene was reported to have a frequency of greater than 7% in melanoma in our previous study. However, its functions remain unclear. Truncated MTAP proteins...

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Detalles Bibliográficos
Autores principales: Lin, Zhuoying, Lei, Yu, Wen, Mingyao, He, Qin, Tian, Dean, Xie, Huaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241944/
https://www.ncbi.nlm.nih.gov/pubmed/37277447
http://dx.doi.org/10.1038/s41598-023-36404-w