Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma

BACKGROUND: Driver alterations may represent novel candidates for driver gene-guided therapy; however, intrahepatic cholangiocarcinoma (ICC) with multiple genomic aberrations makes them intractable. Therefore, the pathogenesis and metabolic changes of ICC need to be understood to develop new treatme...

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Detalles Bibliográficos
Autores principales: Kitagawa, Akihiro, Osawa, Tsuyoshi, Noda, Miwa, Kobayashi, Yuta, Aki, Sho, Nakano, Yusuke, Saito, Tomoko, Shimizu, Dai, Komatsu, Hisateru, Sugaya, Maki, Takahashi, Junichi, Kosai, Keisuke, Takao, Seiichiro, Motomura, Yushi, Sato, Kuniaki, Hu, Qingjiang, Fujii, Atsushi, Wakiyama, Hiroaki, Tobo, Taro, Uchida, Hiroki, Sugimachi, Keishi, Shibata, Kohei, Utsunomiya, Tohru, Kobayashi, Shogo, Ishii, Hideshi, Hasegawa, Takanori, Masuda, Takaaki, Matsui, Yusuke, Niida, Atsushi, Soga, Tomoyoshi, Suzuki, Yutaka, Miyano, Satoru, Aburatani, Hiroyuki, Doki, Yuichiro, Eguchi, Hidetoshi, Mori, Masaki, Nakayama, Keiichi I., Shimamura, Teppei, Shibata, Tatsuhiro, Mimori, Koshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241955/
https://www.ncbi.nlm.nih.gov/pubmed/37076565
http://dx.doi.org/10.1038/s41416-023-02256-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241955/
https://www.ncbi.nlm.nih.gov/pubmed/37076565
http://dx.doi.org/10.1038/s41416-023-02256-4

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