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ATAC-seq reveals the roles of chromatin accessibility in the chondrocytes of Kashin–Beck disease compared with primary osteoarthritis

Objective: This study aimed to investigate the roles of accessible chromatin in understanding the different pathogeneses between Kashin–Beck disease (KBD) and primary osteoarthritis (OA). Methods: Articular cartilages of KBD and OA patients were collected, and after tissue digestion, primary chondro...

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Detalles Bibliográficos
Autores principales: Wang, Sen, Wang, Yuanji, Li, Xingyu, Yuan, Linlin, Guo, Xiong, Lammi, Mikko J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241996/
https://www.ncbi.nlm.nih.gov/pubmed/37287534
http://dx.doi.org/10.3389/fgene.2023.1169417