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Identification and validation of a novel cuproptosis-related stemness signature to predict prognosis and immune landscape in lung adenocarcinoma by integrating single-cell and bulk RNA-sequencing

BACKGROUND: Cancer stem cells (CSCs) play vital roles in lung adenocarcinoma (LUAD) recurrence, metastasis, and drug resistance. Cuproptosis has provided a novel insight into the treatment of lung CSCs. However, there is a lack of knowledge regarding the cuproptosis-related genes combined with the s...

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Detalles Bibliográficos
Autores principales: Yang, Jia, Liu, Kaile, Yang, Lu, Ji, Junqing, Qin, Jingru, Deng, Haibin, Wang, Zhongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242006/
https://www.ncbi.nlm.nih.gov/pubmed/37287976
http://dx.doi.org/10.3389/fimmu.2023.1174762