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A novel benzothiazole derivative induces apoptosis via the mitochondrial intrinsic pathway producing antitumor activity in colorectal cancer

Background: Colorectal cancer (CRC) is one of the most common malignancies causing the third highest mortality rate in the world. It is particularly urgent to explore effective therapeutic strategies to overcome this disease. We identified a novel benzothiazole derivative (BTD) that may serve as a p...

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Detalles Bibliográficos
Autores principales: Zhou, Jing, Zhao, Rongce, Zhou, Haoxuan, Yang, Shuping, Tao, Feiyan, Xie, Yongmei, Wang, Hongli, Yun, Jingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242024/
https://www.ncbi.nlm.nih.gov/pubmed/37288115
http://dx.doi.org/10.3389/fphar.2023.1196158