Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice

INTRODUCTION: Tianeptine is approved in some countries to treat depression and anxiety. In addition to its activity on serotonin and glutamate neurotransmission, tianeptine has been proven to be a mu-opioid receptor (MOR) agonist, but only a few preclinical studies have characterized the opioid-like...

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Detalles Bibliográficos
Autores principales: Allain, Florence, Ehrlich, Aliza T., McNicholas, Michael, Gross, Florence, Ma, Weiya, Kieffer, Brigitte L., Darcq, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242025/
https://www.ncbi.nlm.nih.gov/pubmed/37287667
http://dx.doi.org/10.3389/fpsyt.2023.1186397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242025/
https://www.ncbi.nlm.nih.gov/pubmed/37287667
http://dx.doi.org/10.3389/fpsyt.2023.1186397

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