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Variation in CD8 T cell IFNγ differentiation to strains of Toxoplasma gondii is characterized by small effect QTLs with contribution from ROP16

INTRODUCTION: Toxoplasma gondii induces a strong CD8 T cell response characterized by the secretion of IFNγ that promotes host survival during infection. The initiation of CD8 T cell IFNγ responses in vitro differs widely between clonal lineage strains of T. gondii, in which type I strains are low i...

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Detalles Bibliográficos
Autores principales: Kongsomboonvech, Angel K., García-López, Laura, Njume, Ferdinand, Rodriguez, Felipe, Souza, Scott P., Rosenberg, Alex, Jensen, Kirk D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242045/
https://www.ncbi.nlm.nih.gov/pubmed/37287466
http://dx.doi.org/10.3389/fcimb.2023.1130965