ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache

INTRODUCTION: The high prevalence and severe symptoms of migraines in humans emphasizes the need to identify underlying mechanisms that can be targeted for therapeutic benefit. Clinical Endocannabinoid Deficiency (CED) posits that reduced endocannabinoid tone may contribute to migraine development a...

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Detalles Bibliográficos
Autores principales: Liktor-Busa, Erika, Levine, Aidan A., Palomino, Seph M., Singh, Simar, Wahl, Jared, Vanderah, Todd W., Stella, Nephi, Largent-Milnes, Tally M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pain Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242073/
https://www.ncbi.nlm.nih.gov/pubmed/37287623
http://dx.doi.org/10.3389/fpain.2023.1171188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242073/
https://www.ncbi.nlm.nih.gov/pubmed/37287623
http://dx.doi.org/10.3389/fpain.2023.1171188

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