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Inborn errors of human B cell development, differentiation, and function

B cells develop from hematopoietic stem cells in the bone marrow. Once generated, they serve multiple roles in immune regulation and host defense. However, their most important function is producing antibodies (Ab) that efficiently clear invading pathogens. This is achieved by generating memory B ce...

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Detalles Bibliográficos
Autores principales: Tangye, Stuart G., Nguyen, Tina, Deenick, Elissa K., Bryant, Vanessa L., Ma, Cindy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242086/
https://www.ncbi.nlm.nih.gov/pubmed/37273190
http://dx.doi.org/10.1084/jem.20221105