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GPX2 promotes EMT and metastasis in non‐small cell lung cancer by activating PI3K/AKT/mTOR/Snail signaling axis

Lung cancer, with non‐small cell lung cancer (NSCLC) being the main subtype, is the leading cause of cancer death worldwide, which is mainly due to the cancer metastasis. Glutathione peroxidase 2 (GPX2), an antioxidant enzyme, is involved in tumor progression and metastasis. Nevertheless, the role o...

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Detalles Bibliográficos
Autores principales: Peng, Fang, Xu, Qiushi, Jing, Xiaomeng, Chi, Xinming, Zhang, Zheming, Meng, Xiangpeng, Liu, Xinyuan, Yan, Jiao, Liu, Xuefeng, Shao, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242197/
https://www.ncbi.nlm.nih.gov/pubmed/37287867
http://dx.doi.org/10.1096/fba.2022-00045