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Identification of potential neuroprotective compound from Ganoderma lucidum extract targeting microtubule affinity regulation kinase 4 involved in Alzheimer's disease through molecular dynamics simulation and MMGBSA

OBJECTIVE: Alzheimer's disease (AD) is one of the most prevalent neurological ailments, affecting around 50 million individuals globally. The condition is characterized by nerve cell damage due to the formation of amyloid‐beta plaques and neurofibrillary tangles. Only a few US Food and Drug Adm...

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Detalles Bibliográficos
Autores principales: Ahmad, Faizan, Singh, Gagandeep, Soni, Hemant, Tandon, Smriti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242270/
https://www.ncbi.nlm.nih.gov/pubmed/37287673
http://dx.doi.org/10.1002/agm2.12232