Cargando…

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling

Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, the molecular mediators contributing to vaginal epithelial d...

Descripción completa

Detalles Bibliográficos
Autores principales: Berard, Alicia R., Brubaker, Douglas K., Birse, Kenzie, Lamont, Alana, Mackelprang, Romel D., Noël-Romas, Laura, Perner, Michelle, Hou, Xuanlin, Irungu, Elizabeth, Mugo, Nelly, Knodel, Samantha, Muwonge, Timothy R., Katabira, Elly, Hughes, Sean M., Levy, Claire, Calienes, Fernanda L., Lauffenburger, Douglas A., Baeten, Jared M., Celum, Connie, Hladik, Florian, Lingappa, Jairam, Burgener, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242450/
https://www.ncbi.nlm.nih.gov/pubmed/37149863
http://dx.doi.org/10.1016/j.celrep.2023.112474