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Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA

Farnesoid X receptor (FXR) is a ligand-activated transcription factor known as bile acid receptor (BAR). FXR plays critical roles in various biological processes, including metabolism, immune inflammation, liver regeneration and liver carcinogenesis. FXR forms a heterodimer with the retinoid X recep...

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Detalles Bibliográficos
Autores principales: Jiang, Longying, Liu, Xueke, Liang, Xujun, Dai, Shuyan, Wei, Hudie, Guo, Ming, Chen, Zhuchu, Xiao, Desheng, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242635/
https://www.ncbi.nlm.nih.gov/pubmed/37287811
http://dx.doi.org/10.1016/j.csbj.2023.05.026