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Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA
Farnesoid X receptor (FXR) is a ligand-activated transcription factor known as bile acid receptor (BAR). FXR plays critical roles in various biological processes, including metabolism, immune inflammation, liver regeneration and liver carcinogenesis. FXR forms a heterodimer with the retinoid X recep...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242635/ https://www.ncbi.nlm.nih.gov/pubmed/37287811 http://dx.doi.org/10.1016/j.csbj.2023.05.026 |