Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity

The absence of effective chronic treatment, expansion to non-endemic countries and the significant burden in public health have stimulated the search for novel therapeutic options to treat Chagas disease, a protozoan disease caused by Trypanosoma cruzi. Despite current efforts, no new drug candidate...

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Detalles Bibliográficos
Autores principales: Varela, Marina T., Romanelli, Maiara, Amaral, Maiara, Tempone, Andre G., Fernandes, João Paulo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242637/
https://www.ncbi.nlm.nih.gov/pubmed/37287509
http://dx.doi.org/10.1016/j.jsps.2023.05.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242637/
https://www.ncbi.nlm.nih.gov/pubmed/37287509
http://dx.doi.org/10.1016/j.jsps.2023.05.014

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