Synergistic Li/Li Bimetallic System for the Asymmetric Synthesis of Antituberculosis Drug TBAJ-587

[Image: see text] TBAJ-587, an analogue of the antituberculosis drug bedaquiline (BDQ), bearing a diarylquinoline skeleton retains the high bacterial potency, is less toxic, and has a better pharmacokinetic profile than the parent molecule, which has entered phase I clinical trials. In contrast to i...

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Detalles Bibliográficos
Autores principales: Ahmad, Tanveer, Gao, Feng, Li, Jing, Zhang, Zhenfeng, Song, Tao, Yuan, Qianjia, Zhang, Wanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242759/
https://www.ncbi.nlm.nih.gov/pubmed/37125776
http://dx.doi.org/10.1021/acs.joc.3c00705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242759/
https://www.ncbi.nlm.nih.gov/pubmed/37125776
http://dx.doi.org/10.1021/acs.joc.3c00705

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