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Access to Spiropyrazolone-butenolides through NHC-Catalyzed [3 + 2]-Asymmetric Annulation of 3-Bromoenals and 1H-Pyrazol-4,5-diones

[Image: see text] The stereoselective synthesis of spirocyclic pyrazolin-5-ones by N-heterocyclic carbene (NHC) organocatalysis has been less studied so far. For this reason and considering the interest of this class of compounds, here, we present the NHC-catalyzed [3 + 2]-asymmetric annulation of β...

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Detalles Bibliográficos
Autores principales: Gil-Ordóñez, Marta, Maestro, Alicia, Andrés, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242763/
https://www.ncbi.nlm.nih.gov/pubmed/37167601
http://dx.doi.org/10.1021/acs.joc.3c00188