miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto’s thyroiditis

BACKGROUND: Hashimoto’s thyroiditis (HT) is an organ-specific autoimmune disease characterized by lymphocyte infiltration that destroys thyrocyte cells. The aim of the present study was to elucidate the role and mechanisms of tissue small extracellular vesicle (sEV) microRNAs (miRNAs) in the pathoge...

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Detalles Bibliográficos
Autores principales: Li, Genpeng, He, Linye, Huang, Jing, Liu, Jiaye, Chen, Wenjie, Zhong, Jinjing, Wei, Tao, Li, Zhihui, Zhu, Jingqiang, Lei, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242775/
https://www.ncbi.nlm.nih.gov/pubmed/37280674
http://dx.doi.org/10.1186/s12916-023-02914-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242775/
https://www.ncbi.nlm.nih.gov/pubmed/37280674
http://dx.doi.org/10.1186/s12916-023-02914-7

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