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miR-142-3p encapsulated in T lymphocyte-derived tissue small extracellular vesicles induces Treg function defect and thyrocyte destruction in Hashimoto’s thyroiditis
BACKGROUND: Hashimoto’s thyroiditis (HT) is an organ-specific autoimmune disease characterized by lymphocyte infiltration that destroys thyrocyte cells. The aim of the present study was to elucidate the role and mechanisms of tissue small extracellular vesicle (sEV) microRNAs (miRNAs) in the pathoge...
Autores principales: | Li, Genpeng, He, Linye, Huang, Jing, Liu, Jiaye, Chen, Wenjie, Zhong, Jinjing, Wei, Tao, Li, Zhihui, Zhu, Jingqiang, Lei, Jianyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242775/ https://www.ncbi.nlm.nih.gov/pubmed/37280674 http://dx.doi.org/10.1186/s12916-023-02914-7 |
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