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Single‐cell characteristics and malignancy regulation of alpha‐fetoprotein‐producing gastric cancer

OBJECTIVE: To characterize alpha‐fetoprotein (AFP)‐producing gastric cancer (AFPGC) at the single‐cell level and to identify regulatory factors for AFP expression and malignancy. METHODS: ScRNA‐seq was performed on two tumors collected from patients with AFPGC. InferCNV and sub‐clustering were appli...

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Detalles Bibliográficos
Autores principales: Mei, Yanxia, Li, Ming, Wen, Jihang, Kong, Xiangxing, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242870/
https://www.ncbi.nlm.nih.gov/pubmed/37017469
http://dx.doi.org/10.1002/cam4.5883