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MicroRNA-27a-3p enhances the inflammatory phenotype of Juvenile Idiopathic Arthritis fibroblast-like synoviocytes

BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic pediatric rheumatic disorder. In joints of JIA patients, aggressive phenotypic changes in fibroblast-like synoviocytes (FLS) of the synovial lining play a key role in inflammation. MicroRNAs are dysregulated in rheumatoid...

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Detalles Bibliográficos
Autores principales: Bullock, Claire H., McAlpine, Sarah M., Roberts, Sarah E., Derfalvi, Beata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243012/
https://www.ncbi.nlm.nih.gov/pubmed/37277817
http://dx.doi.org/10.1186/s12969-023-00833-8