Increased METTL3 expression and m(6)A RNA methylation may contribute to the development of dry eye in primary Sjögren’s syndrome

BACKGROUND: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder defined by xerostomia and keratoconjunctivitis sicca, and its etiology remains unknown. N6-methyladenosine (m(6)A) is the predominant posttranscriptional modification in eukaryotic mRNAs and is dynamically regulated by m(6...

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Detalles Bibliográficos
Autores principales: Ma, Jun, Wang, Xiaotang, Yang, Xue, Wang, Xi, Tan, Tongshan, Fang, Hongping, Zhong, Yu, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243060/
https://www.ncbi.nlm.nih.gov/pubmed/37277716
http://dx.doi.org/10.1186/s12886-023-02988-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243060/
https://www.ncbi.nlm.nih.gov/pubmed/37277716
http://dx.doi.org/10.1186/s12886-023-02988-0

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