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Increased METTL3 expression and m(6)A RNA methylation may contribute to the development of dry eye in primary Sjögren’s syndrome

BACKGROUND: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disorder defined by xerostomia and keratoconjunctivitis sicca, and its etiology remains unknown. N6-methyladenosine (m(6)A) is the predominant posttranscriptional modification in eukaryotic mRNAs and is dynamically regulated by m(6...

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Detalles Bibliográficos
Autores principales:	Ma, Jun, Wang, Xiaotang, Yang, Xue, Wang, Xi, Tan, Tongshan, Fang, Hongping, Zhong, Yu, Zhang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243060/ https://www.ncbi.nlm.nih.gov/pubmed/37277716 http://dx.doi.org/10.1186/s12886-023-02988-0

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