One-Pot, Telescoped Alkenylation of Amides via Stable Tetrahedral Intermediates as Lithium Enolate Precursors

[Image: see text] A mild and efficient telescoped procedure for the stereoselective alkenylation of simple, non-activated amides using LiCH(2)SiMe(3) and carbonyl compounds as surrogates of alkenyllithium reagents is reported. Our methodology relies on the formation of stable tetrahedral intermediat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghinato, Simone, Meazzo, Carolina, De Nardi, Federica, Maranzana, Andrea, Blangetti, Marco, Prandi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243110/
https://www.ncbi.nlm.nih.gov/pubmed/37218660
http://dx.doi.org/10.1021/acs.orglett.3c01269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243110/
https://www.ncbi.nlm.nih.gov/pubmed/37218660
http://dx.doi.org/10.1021/acs.orglett.3c01269

Ejemplares similares