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Tuo-Min-Ding-Chuan Decoction Alleviates Airway Inflammations in the Allergic Asthmatic Mice Model by Regulating TLR4-NLRP3 Pathway-Mediated Pyroptosis: A Network Pharmacology and Experimental Verification Study

BACKGROUND: Tuo-Min-Ding-Chuan Decoction (TMDCD) is an effective traditional Chinese medicine (TCM) formula granule for allergic asthma (AA). Previous studies proved its effects on controlling airway inflammations, while the specific mechanism was not clear. METHODS: We conducted a network pharmacol...

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Detalles Bibliográficos
Autores principales: Lyu, Mingsheng, Qin, Jingbo, Huang, Shuaiyang, Shao, Dongmei, Huang, Guirui, Yang, Fan, Gong, Xuefeng, Zhang, Shiyu, Zhang, Zhijie, Wang, Ji, Cui, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243359/
https://www.ncbi.nlm.nih.gov/pubmed/37287697
http://dx.doi.org/10.2147/DDDT.S406483