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Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates

BACKGROUND: Mycobacterium abscessus subspecies massiliense (M. massiliense) is increasingly recognized as an emerging bacterial pathogen, particularly in cystic fibrosis (CF) patients and CF centres’ respiratory outbreaks. We characterized genomic and phenotypic changes in 15 serial isolates from tw...

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Detalles Bibliográficos
Autores principales: Shallom, Shamira J., Tettelin, Hervé, Chandrasekaran, Prabha, Park, In Kwon, Agrawal, Sonia, Arora, Kriti, Sadzewicz, Lisa, Milstone, Aaron M., Aitken, Moira L., Brown-Elliott, Barbara A., Wallace, Richard J., Sampaio, Elizabeth P., Niederweis, Michael, Olivier, Kenneth N., Holland, Steven M., Zelazny, Adrian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243398/
https://www.ncbi.nlm.nih.gov/pubmed/37221835
http://dx.doi.org/10.1080/21505594.2023.2215602