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Interactome Analysis of the ER Stress Sensor Perk Uncovers Key Components of ER-Mitochondria Contact Sites and Ca(2+) Signalling
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER– plasma membrane (ER-PM) contact sites, independent of its canonical role in the unfolded protein response. PERK regulation of ER-PM contacts was revealed by a proximity biotinylation (BioID) approach an...
Autores principales: | Sassano, Maria Livia, Derua, Rita, Waelkens, Etienne, Agostinis, Patrizia, van Vliet, Alexander R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243573/ https://www.ncbi.nlm.nih.gov/pubmed/37366380 http://dx.doi.org/10.1177/25152564211052392 |
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