Treatment effect modification due to comorbidity: Individual participant data meta-analyses of 120 randomised controlled trials

BACKGROUND: People with comorbidities are underrepresented in clinical trials. Empirical estimates of treatment effect modification by comorbidity are lacking, leading to uncertainty in treatment recommendations. We aimed to produce estimates of treatment effect modification by comorbidity using ind...

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Detalles Bibliográficos
Autores principales: Hanlon, Peter, Butterly, Elaine W., Shah, Anoop SV, Hannigan, Laurie J., Lewsey, Jim, Mair, Frances S., Kent, David M., Guthrie, Bruce, Wild, Sarah H., Welton, Nicky J., Dias, Sofia, McAllister, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243630/
https://www.ncbi.nlm.nih.gov/pubmed/37279199
http://dx.doi.org/10.1371/journal.pmed.1004176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243630/
https://www.ncbi.nlm.nih.gov/pubmed/37279199
http://dx.doi.org/10.1371/journal.pmed.1004176

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