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Treatment effect modification due to comorbidity: Individual participant data meta-analyses of 120 randomised controlled trials
BACKGROUND: People with comorbidities are underrepresented in clinical trials. Empirical estimates of treatment effect modification by comorbidity are lacking, leading to uncertainty in treatment recommendations. We aimed to produce estimates of treatment effect modification by comorbidity using ind...
Autores principales: | Hanlon, Peter, Butterly, Elaine W., Shah, Anoop SV, Hannigan, Laurie J., Lewsey, Jim, Mair, Frances S., Kent, David M., Guthrie, Bruce, Wild, Sarah H., Welton, Nicky J., Dias, Sofia, McAllister, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243630/ https://www.ncbi.nlm.nih.gov/pubmed/37279199 http://dx.doi.org/10.1371/journal.pmed.1004176 |
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