Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity

Cisplatin is a widely used chemotherapy drug; however, it induces both acute and chronic kidney diseases (CKD) in patients with cancer. The pathogenesis of cisplatin-induced CKD is unclear, and effective renoprotective approaches are not available. Here, we report that repeated low-dose cisplatin (R...

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Detalles Bibliográficos
Autores principales: Li, Siyao, Livingston, Man J., Ma, Zhengwei, Hu, Xiaoru, Wen, Lu, Ding, Han-Fei, Zhou, Daohong, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243740/
https://www.ncbi.nlm.nih.gov/pubmed/36917180
http://dx.doi.org/10.1172/jci.insight.166643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243740/
https://www.ncbi.nlm.nih.gov/pubmed/36917180
http://dx.doi.org/10.1172/jci.insight.166643

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