GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

Glycolysis is central to homeostasis of nucleus pulposus (NP) cells in the avascular intervertebral disc. Since the glucose transporter, GLUT1, is a highly enriched phenotypic marker of NP cells, we hypothesized that it is vital for the development and postnatal maintenance of the disc. Surprisingly...

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Detalles Bibliográficos
Autores principales: Johnston, Shira N., Silagi, Elizabeth S., Madhu, Vedavathi, Nguyen, Duc H., Shapiro, Irving M., Risbud, Makarand V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243741/
https://www.ncbi.nlm.nih.gov/pubmed/36917198
http://dx.doi.org/10.1172/jci.insight.164883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243741/
https://www.ncbi.nlm.nih.gov/pubmed/36917198
http://dx.doi.org/10.1172/jci.insight.164883

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