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How to initiate tissue regeneration by generating mutually exclusive cell states

A healing wound is made of cells that paused proliferation and secrete mitogenic factors and cells that proliferate to replace those lost to cell death. A new study in PLOS Biology describes how 2 conserved signaling pathways could repress each other to create these mutually exclusive cell states.

Detalles Bibliográficos
Autor principal: Su, Tin Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243753/
https://www.ncbi.nlm.nih.gov/pubmed/37279465
http://dx.doi.org/10.1371/journal.pbio.3002155