Cargando…

How to initiate tissue regeneration by generating mutually exclusive cell states

A healing wound is made of cells that paused proliferation and secrete mitogenic factors and cells that proliferate to replace those lost to cell death. A new study in PLOS Biology describes how 2 conserved signaling pathways could repress each other to create these mutually exclusive cell states.

Detalles Bibliográficos
Autor principal: Su, Tin Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243753/
https://www.ncbi.nlm.nih.gov/pubmed/37279465
http://dx.doi.org/10.1371/journal.pbio.3002155
_version_ 1785054490036011008
author Su, Tin Tin
author_facet Su, Tin Tin
author_sort Su, Tin Tin
collection PubMed
description A healing wound is made of cells that paused proliferation and secrete mitogenic factors and cells that proliferate to replace those lost to cell death. A new study in PLOS Biology describes how 2 conserved signaling pathways could repress each other to create these mutually exclusive cell states.
format Online
Article
Text
id pubmed-10243753
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-102437532023-06-07 How to initiate tissue regeneration by generating mutually exclusive cell states Su, Tin Tin PLoS Biol Primer A healing wound is made of cells that paused proliferation and secrete mitogenic factors and cells that proliferate to replace those lost to cell death. A new study in PLOS Biology describes how 2 conserved signaling pathways could repress each other to create these mutually exclusive cell states. Public Library of Science 2023-06-06 /pmc/articles/PMC10243753/ /pubmed/37279465 http://dx.doi.org/10.1371/journal.pbio.3002155 Text en © 2023 Tin Tin Su https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Primer
Su, Tin Tin
How to initiate tissue regeneration by generating mutually exclusive cell states
title How to initiate tissue regeneration by generating mutually exclusive cell states
title_full How to initiate tissue regeneration by generating mutually exclusive cell states
title_fullStr How to initiate tissue regeneration by generating mutually exclusive cell states
title_full_unstemmed How to initiate tissue regeneration by generating mutually exclusive cell states
title_short How to initiate tissue regeneration by generating mutually exclusive cell states
title_sort how to initiate tissue regeneration by generating mutually exclusive cell states
topic Primer
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243753/
https://www.ncbi.nlm.nih.gov/pubmed/37279465
http://dx.doi.org/10.1371/journal.pbio.3002155
work_keys_str_mv AT sutintin howtoinitiatetissueregenerationbygeneratingmutuallyexclusivecellstates