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Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer

Inhibition of androgen receptor (AR) signaling has been the mainstay of treatment of advanced prostate cancer (PCa) for the past 80 years. Combination and sequential AR-inhibiting therapies are highly effective palliative therapy, but they are not curative. All patients eventually develop resistance...

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Detalles Bibliográficos
Autores principales: Denmeade, Samuel R, Sena, Laura A, Wang, Hao, Antonarakis, Emmanuel S, Markowski, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243791/
https://www.ncbi.nlm.nih.gov/pubmed/37027449
http://dx.doi.org/10.1093/oncolo/oyad055