Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis

Vascular smooth muscle–derived Sca1(+) adventitial progenitor (AdvSca1-SM) cells are tissue-resident, multipotent stem cells that contribute to progression of vascular remodeling and fibrosis. Upon acute vascular injury, AdvSca1-SM cells differentiate into myofibroblasts and are embedded in perivasc...

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Detalles Bibliográficos
Autores principales: Jolly, Austin J., Lu, Sizhao, Dubner, Allison M., Strand, Keith A., Mutryn, Marie F., Pilotti-Riley, Aaron, Danis, Etienne P., Nemenoff, Raphael A., Moulton, Karen S., Majesky, Mark W., Weiser-Evans, Mary C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243795/
https://www.ncbi.nlm.nih.gov/pubmed/36976650
http://dx.doi.org/10.1172/jci.insight.164862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243795/
https://www.ncbi.nlm.nih.gov/pubmed/36976650
http://dx.doi.org/10.1172/jci.insight.164862

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