Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is characterized by multisystem, low-grade neoplasia involving the lung, kidneys, brain, and heart. Lymphangioleiomyomatosis (LAM) is a progressive pulmonary disease affecting almost exclusively women. TSC and LAM are both caused by mutations in TSC1 and TSC2 that re...

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Detalles Bibliográficos
Autores principales: Astrinidis, Aristotelis, Li, Chenggang, Zhang, Erik Y., Zhao, Xueheng, Zhao, Shuyang, Guo, Minzhe, Olatoke, Tasnim, Mattam, Ushodaya, Huang, Rong, Zhang, Alan G., Pitstick, Lori, Kopras, Elizabeth J., Gupta, Nishant, Jandarov, Roman, Smith, Eric P., Fugate, Elizabeth, Lindquist, Diana, Markiewski, Maciej M., Karbowniczek, Magdalena, Wikenheiser-Brokamp, Kathryn A., Setchell, Kenneth D. R., McCormack, Francis X., Xu, Yan, Yu, Jane J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243802/
https://www.ncbi.nlm.nih.gov/pubmed/36927688
http://dx.doi.org/10.1172/jci.insight.166850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243802/
https://www.ncbi.nlm.nih.gov/pubmed/36927688
http://dx.doi.org/10.1172/jci.insight.166850

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