FRC transplantation restores lymph node conduit defects in laminin α4–deficient mice

Fibroblastic reticular cells (FRCs) play important roles in tolerance by producing laminin α4 (Lama4) and altering lymph node (LN) structure and function. The present study revealed the specific roles of extracellular matrix Lama4 in regulating LN conduits using FRC-specific KO mouse strains. FRC-de...

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Detalles Bibliográficos
Autores principales: Li, Lushen, Wu, Long, Kensiski, Allison, Zhao, Jing, Shirkey, Marina W., Song, Yang, Piao, Wenji, Zhang, Tianshu, Mei, Zhongcheng, Gavzy, Samuel J., Ma, Bing, Saxena, Vikas, Lee, Young S., Xiong, Yanbao, Li, Xiaofei, Fan, Xiaoxuan, Abdi, Reza, Bromberg, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243809/
https://www.ncbi.nlm.nih.gov/pubmed/37092548
http://dx.doi.org/10.1172/jci.insight.167816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243809/
https://www.ncbi.nlm.nih.gov/pubmed/37092548
http://dx.doi.org/10.1172/jci.insight.167816

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